[Frontiers in Bioscience 8, d279-285, January 1, 2003] 279 TRANSCRIPTION FACTOR AS A TOPOLOGICAL HOMEOSTAT
نویسندگان
چکیده
1. Abstract 2. Introduction 3. Effects of FIS binding on DNA structure 3.1. Global effect of FIS binding to supercoiled DNA 3.2. Local effect of FIS binding to promoter upstream regions 4. Regulation of promoter activity by FIS 4.1. Mechanistic relationship between the effects of FIS and supercoiling 4.2. Role of the DNA microloop 5. Mechanism of transcriptional activation by FIS 6. FIS as a topological optimiser 7. Acknowledgements 8. References
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